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Ibuprofen is a weaker anti-inflammatory agent than other NSAIDs. Like other NSAIDs, it works by inhibiting the production of prostaglandins by decreasing the activity of the enzyme cyclooxygenase (COX). While it is unclear whether it is safe in early pregnancy, it appears to be harmful in later pregnancy and therefore is not recommended. At low doses, it does not appear to increase the risk of heart attack however, at higher doses it may.

It increases the risk of heart failure, kidney failure, and liver failure. Compared to other NSAIDs, it may have other side effects such as gastrointestinal bleeding. Ĭommon side effects include heartburn and a rash. It typically begins working within an hour. It can be used by mouth or intravenously. It may also be used to close a patent ductus arteriosus in a premature baby. This includes painful menstrual periods, migraines, and rheumatoid arthritis. We will also determine if there is an interval difference from time of analgesia administration to perception of analgesia that is clinically significant.Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is used for treating pain, fever, and inflammation. The purpose of this study is to assess whether ibuprofen in suspension form results in relief of pain more quickly than the tablet form of an equivalent dose of ibuprofen. This is a double blinded randomized placebo controlled trial to compare suspension versus tablet ibuprofen in an emergency department population presenting with sore throat. To date, no study has evaluated onset to analgesia as reported by the patient for suspension versus tablet formation of ibuprofen in an emergency department population presenting with complaints of sore throat. Several studies have demonstrated that ibuprofen in suspension is absorbed into the system more quickly and results in earlier maximum blood concentrations.

Sore throat has been established to be an acceptable model of analgesic effect, and ibuprofen has been found to offer relief in studies of sore throat. Ibuprofen is known to be an effective treatment for many forms of pain. Pain is a common emergency and urgent care complaint. Why Should I Register and Submit Results?.